Skip to Main Content
It looks like you're using Internet Explorer 11 or older. This website works best with modern browsers such as the latest versions of Chrome, Firefox, Safari, and Edge. If you continue with this browser, you may see unexpected results.
Clinical Practice Guidelines (CPGs)
Clinical practice guidelines (CPGs) are evidence-based recommendations designed to help health care professionals make clinical decisions. This page overviews databases and appraisal tools relevant to the world of CPGs.
The Health Council of Canada's series of videos:
- These short videos provide an overview of CPGs in Canada through the eyes of those who design, disseminate, and use this type of evidence.
Clinical Practice Guidelines (CPGs) - Critical Appraisal Tools
AGREE II-GRS Instrument
A 5 item rating scale used to evaluate the quality and reporting of clinical practice guidelines. While the AGREE II remains the recommended appraisal tool for clinical practice guidelines, the AGREE II-GRS Instrument is a practical alternative, especially when time and resources are limited
This tool consists of 23 items organized within 6 domains followed by 2 global rating items (“Overall Assessment”) to assess the quality of a clinical practice guideline.
Find Clinical Practice Guidelines (CPGs)
Canadian Medical Association (CMA) Infobase: Clinical Practice Guidelines Database (CPGs)
Canada's database of clinical practice guidelines. Search or browse by developer, condition, specialty, recently added, or title. All guidelines were produced or endorsed in Canada by a national, provincial or territorial medical or health organization, professional society, government agency or expert panel.
Cancer Guidelines Database
Access to thousands of Canadian and international cancer guidelines, all in a single database. Quality scores for guidelines (using the AGREE II tool) to ensure that you have the best available evidence from credible sources.
Guidelines from 35+ medical societies and government agencies. Some are free and some require payment in order to access.
TRIP covers guidelines from North America, Europe and internationally. Select 'Guidelines' filter on results page to limit to practice guidelines.
NICE: National Institute for Health and Care Excellence (U.K.)
British clinical guidelines authored by NICE. Search by keyword, or explore by subject area.
National Health and Medical Research Council (Australia)
Over 2400 clinical practice guidelines developed for use in Australian healthcare settings.
The Centre for Effective Practice
The Centre for Effective Practice is a national not-for-profit organization, whose mission is to close the gap between evidence and practice for healthcare providers. It contains clinical tools and resources for providers.
National Kidney Foundation Guidelines
Guidelines on topics like acute kidney injury, anemia, nutrition in CKD, hemodialysis adequacy, etc.
The American College of Chest Physicians Guidelines
Guidelines on topics like airway disorders, chest infections, pulmonary vascular disease, thoracic oncology, etc.
Hypertension Canada (CHEP) Guidelines
Guidelines on diagnosis, assessment, prevention and treatment.
Association of Medical Microbiology and Infectious Disease Canada
Guidelines developed or endorsed by AMMI on topics like ebola, zika virus, antiviral drugs for influenza, etc.
Infectious Diseases Society of America (IDSA) Guidelines
Guidelines on topics like candidiasis, antimicrobial stewardship, c.difficile, community-acquired pneumonia, COVID-19, encephalitis, endocarditis, lyme disease, HIV care, etc.
Cancer Care Ontario (PEBC) Guidelines
Guidelines on all types of cancers, from diagnosis to treatment, and modality of care (e.g. surveillance, chemotherapy, surgery, radiation, etc.).
American Society of Clinical Oncology
Guidelines by clinical area: assays and predictive markers; breast cancer; gastrointestinal cancer; genitourinary cancer; gynecologic cancer; head & neck cancer; hematologic cancer; thoracic cancer; melanoma; neurooncology, etc.
European Society for Medical Oncology
Guidelines on different types of cancers and cancer patient management during the COVID-19 pandemic.
Canadian Diabetes Association (CDA) Guidelines
Guidelines on screening, glycemic control, physical activity, nutrition therapy, hypoglycemia, weight management, mental health, dyslipidemia, retinopathy, foot care, pregnancy, type II diabetes and Indigenous Peoples, etc.
Canadian Thoracic Society Guidelines
Guidelines and position statements on topics like asthma, COPD, face masks, pulmonary function testing, mechanical ventilation, interstitial lung disease, sleep disorders, etc.
Canadian Cardiovascular Society Guidelines
Guidelines and position statements on topics like atrial fibrillation, arrhythmia, heart disease, heart failure, syncope, antiplatelet therapy, cardiac arrest, dyslipidemia, etc.
Thrombosis Canada Guidelines
Guidelines on topics like antiplatelet therapy, management of atrial fibrillation, anti-thrombotic therapy, etc.
Society of Critical Care Medicine
Clinical and administrative guidelines on topics like sepsis, chronic liver failure, ICU admission and discharge, managing patients in the ICU, etc.